https://en.wikipedia.org/wiki/Microneedles

MicroneedleCov cuab yeej kho mob tam sim no nyob rau hauv qhov kev hloov pauv tseem ceeb los ntawm kev tshwj xeeb kom nkag mus tau rau cov pej xeem. Kev ua lag luam thoob ntiaj teb muaj kev loj hlob txhua xyoo ntau dua 15%, thiab nws xav tias qhov ntsuas yuav ntau dua 5 billion US dollars los ntawm 2030. Lub khw loj no tau nyiam ntau tus neeg ua si, txij li pib- nce mus rau ntau lub teb chaws kws tshuaj thiab cov cuab yeej siv kho mob loj, uas txhua tus ua lawv nkag.

Cov toj roob hauv pes kev ua lag luam tam sim no qhia txog peb - theem sib txawv. Thawj qib muaj cov khoom siv siab tshaj - kawg, xws li xov tooj cua zaus microneedles thiab cov tshuab ntse microneedle, nrog rau cov nqi txij li kaum tawm txhiab mus rau ntau pua txhiab RMB, feem ntau yog tsom rau cov tsev kho mob thiab cov tsev kho mob loj. Cov neeg sawv cev muaj xws li Synolong thiab Kemosun. Qib thib ob yog nruab nrab -ntau yam semi- cov cuab yeej tshaj lij, xws li hluav taws xob microneedle cwjmem, nrog cov nqi ntawm ntau txhiab yuan, dav siv hauv me me thiab nruab nrab- cov chaw kho mob loj thiab chaw tswj xyuas tawv nqaij. Qhov thib peb yog cov khoom siv hauv tsev, suav nrog nano- phaj rollers thiab microneedle daim npog qhov ncauj thaj ua rau thaj, nrog rau cov nqi txij li ntau lub kaum os yuan mus rau ntau pua yuan, feem ntau yog muag los ntawm e- kev lag luam channel, tsom rau cov neeg siv khoom nrhiav ntawm - kev saib xyuas hauv tsev.

Lub tsev -siv ntu yog qhov nrawm tshaj plaws - kev lag luam loj hlob. Raws li cov neeg siv khoom paub txog "kev tu tawv nqaij zoo" nce, ntau thiab ntau tus neeg cia siab tias yuav tau txais kev tshaj lij- qib kev saib xyuas hauv tsev. Cov cuab yeej microneedle hauv tsev yuav tsum tau hais txog ob lub ntsiab lus mob loj: kev nyab xeeb thiab kev ua tau zoo. Hais txog kev nyab xeeb, rab koob ntev yog nruj me ntsis txwv tsis pub qis dua 0.3mm kom ntseeg tau tias nws tsis ua mob rau lub dermis txheej; Nyob rau hauv cov nqe lus ntawm kev ua tau zoo, cov khoom siv nrog cov ntsiab lus tseem ceeb tau tsim tshwj xeeb los ua haujlwm hauv kev sib koom ua ke nrog cov microneedle raws. Tam sim no, Kaus Lim Kauslim thiab Suav cov hom lag luam tau tswj hwm lub tsev lag luam microneedle, thiab lawv cov khoom hloov kho thiab rov ua dua tau nrawm heev.

Lub hom phiaj ntawm kev siv technology tshiab yog nyob rau hauv plaub qhov loj me.

1. Cov khoom siv tshiab.Tshiab biodegradable polymers, hydrogels, thiab silk fibroin yog siv los tsim microneedles. Cov ntaub ntawv no muaj biocompatibility zoo heev thiab tswj tau degradation tus nqi. Qee tus ntawm lawv tuaj yeem nqa cov qia cell exosomes lossis cov yam ntxwv loj hlob, ua tiav qib kev kho mob piv rau cov tshuaj kho dua tshiab.
2. Kev txawj ntse.Qhov ntse microneedle thaj, uas sib txuas cov sensors, Bluetooth chips, thiab cov roj teeb me me, tab tom txav ntawm chav kuaj mus rau ntau lawm. Cov neeg siv tuaj yeem sau lub sijhawm, qhov chaw, thiab qhov tob ntawm txhua qhov kev kho mob los ntawm lub xov tooj ntawm tes app, thiab lub cuab yeej tseem tuaj yeem pom zoo rau txoj kev kho mob zoo tshaj plaws raws li qhov mob ntawm daim tawv nqaij.
3. Kev kho ua ke.Cov cuab yeej microneedle tsis ua haujlwm ntawm nws tus kheej, tab sis ua ke nrog lub cev muaj zog xws li kev kho lub teeb, hluav taws xob stimulation, thiab ultrasound. Piv txwv li, cov cuab yeej sib txuas microneedles nrog LED kev kho teeb pom kev zoo ua kom muaj kev sib koom ua ke ntawm kev tiv thaiv - muaj peev xwm kho thiab kho.
4. Tus kheej customization.Los ntawm leveraging 3D scanning thiab 3D tshuab luam ntawv technologies, yav tom ntej microneedle pab kiag li lawm yuav ua tau raws li ib tug tshwj xeeb kev npaj thiab tob tis ntawm cov koob raws li ib tug neeg lub ntsej muag contours, daim tawv nqaij thickness, thiab qhov chaw ntawm qhov txhab, yog li ua tiav cov tshuaj precision.

Kev tswj hwm ib puag ncig kuj maj mam txhim kho. Tuam Tshoj National Medical Products Administration tau txheeb xyuas qee cov khoom siv microneedle ua cov cuab yeej siv kho mob Class II thiab xav kom lawv tau txais kev soj ntsuam kuaj mob thiab kuaj kev sau npe. European Union thiab US FDA kuj tau tshaj tawm cov lus qhia sib xws. Cov kev cai ruaj khov pab tshem tawm cov khoom tsis zoo thiab txhawb kev noj qab haus huv ntawm kev lag luam.

Lub neej yav tom ntej ntawm microneedle cov cuab yeej kho mob tsis yog tsuas yog hais txog "cov koob zoo dua," tab sis yog ib qho kev qhia dav dav uas suav nrog kev kuaj mob, kev kho mob, thiab kev saib xyuas. Thaum cov cuab yeej no dhau los ua neeg ntse txaus, muaj kev nyab xeeb txaus, thiab pheej yig txaus, lawv yuav, zoo li niaj hnub smartphones, dhau los ua phooj ywg txhua hnub rau kev tswj hwm kev noj qab haus huv.