Biocompatibility Breakthrough: Parylene Coated Hypotubes Rau Implantable Devices

Taw qhia: Qhov Kev Sib Tw Biocompatibility

Thaum hypotubes siv rau hauv cov khoom siv cog qoob loo lossis kev cuam tshuam ntev -, lub cev cov tshuaj tiv thaiv rau cov khoom txawv teb chaws dhau los ua qhov mob hnyav. Bare stainless hlau los yog Nitinol tuaj yeem tshem tawm ions, ua rau mob, lossis ua rau mob thrombosis. Qhov no tsis tuaj yeem lees txais hauv cov ntawv thov xws li cov hlab plawv stents lossis tso zis tso zis. Qhov kev xav tau ntawm biocompatible barrier uas tsis cuam tshuam qhov kev ua haujlwm ntawm lub laser txiav hypotube yog qhov tseem ceeb.

Txoj Cai: Parylene's Biostable Barrier

Parylene yog inherently biostable thiab biocompatible, ua tau raws li USP Class VI thiab ISO 10993 cov cai. Lub hauv paus ntsiab lus ntawm nws cov kev ua tau zoo yog nyob rau hauv nws lub peev xwm los tsim ib tug conformal, pinhole -dawb thaiv nyob ib ncig ntawm lub hypotube. Qhov teeb meem no tiv thaiv ion leaching thiab txo cov protein adsorption, txo txoj kev pheej hmoo ntawm cov ntshav txhaws. Cov txheej txheem dielectric kuj tseem thaiv cov hlau los ntawm cov kua dej hauv lub cev, tiv thaiv galvanic corrosion. Rau ib lub laser txiav hypotube, qhov no txhais tau hais tias cov qauv txiav intricate yog tiv thaiv yam tsis hloov lawv yooj yim los yog torque, raws li cov txheej yog thov nyob rau hauv ib tug molecular theem.

Kev faib khoom siv rau kev ruaj ntseg zoo

Txhawm rau kom ntseeg tau tias biocompatibility, cov cuab yeej siv yuav tsum mus dhau qhov kev tso tawm tus qauv. Chav kawm 100,000 chav huv yuav tsum muaj rau txheej txheej txheej txheej kom tsis txhob muaj cov kab mob sib kis. Cov txheej txheem tso nyiaj yuav tsum tau nruab nrog kev pom zoo thiab kev saib xyuas kom tswj tau qhov chaw tsis muaj menyuam. Tsis tas li ntawd, cov cuab yeej kuaj xyuas xws li scanning electron microscopes (SEM) rau txheej kev ncaj ncees thiab tribometers rau kev ntsuas kev sib txhuam yog qhov tseem ceeb. Cov cuab yeej no txheeb xyuas tias Parylene coated hypotube ua tau raws li cov kev cai nruj ntawm ISO 13485 rau cov khoom siv kho mob.

Phau Ntawv Qhia Txog Tswv Yim: Ua kom muaj kev sib haum xeeb

Cov kauj ruam ua tau zoo pib nrog xaiv yam Parylene txoj cai-feem ntau Parylene C rau nws cov khoom thaiv zoo heev. Lub hypotube, txawm tias 304 los yog 316L stainless hlau, yuav tsum tau muab ntxuav kom huv si thiab passivated. Cov txheej txheem txheej yuav tsum raug muab pov thawj kom ntseeg tau tias tsis muaj cytotoxic residues nyob. Tom qab- txheej, cov khoom tau ntim rau hauv cov thawv ntim khoom lossis kev cai kho mob- qib ntim kom tsis txhob muaj menyuam. Cov ntaub ntawv ntawm tag nrho cov txheej txheem, los ntawm cov ntaub ntawv pov thawj raw khoom mus rau qhov kev soj ntsuam zaum kawg, yog qhov tseem ceeb rau kev tswj xyuas cov ntaub ntawv.

Tiag -Kev Paub Txog Ntiaj Teb: Cov Dab Neeg Ua Haujlwm Zoo

Hauv peb lub Hoobkas, peb tau tsim Parylene coated hypotubes rau cov neeg siv khoom tsim tom ntej -cov khoom siv endoscopic. Ib txoj haujlwm tseem ceeb cuam tshuam nrog kev xa cov hlab plawv uas lub raj coated qhia xoom cov cim ntawm kev xeb tom qab kev kuaj kev laus sai. Cov kws kho mob tau tshaj tawm tias kev xa khoom yooj yim dua thiab txo cov sijhawm ua haujlwm. Peb kuj tau kawm tias txheej txheej xim (me ntsis translucency) tuaj yeem cuam tshuam rau kev kuaj pom; Yog li, peb tau siv backlighting thaum lub sijhawm kuaj xyuas kom tsis muaj qhov tsis zoo.

Xaus thiab Sublimation

Parylene txheej elevates lub laser txiav hypotube los ntawm ib tug mere mechanical tivthaiv mus rau ib tug biologically inert, lub neej - txuag cuab yeej. Nws txuas qhov sib txawv ntawm engineering zoo tshaj plaws thiab kev sib haum xeeb lom neeg. Qhov kev rhuav tshem no tsis yog tsuas yog txhim kho cov cuab yeej siv tau ntev, tab sis kuj tseem txhim kho cov neeg mob kev nyab xeeb, ua rau lub sijhawm tshiab hauv kev siv tshuab kho mob uas lub cev lees txais cov cuab yeej ua qhov txuas ntxiv ntawm nws tus kheej.

Cov kev cia siab thiab cov lus pom zoo

Raws li txoj kev kho mob txav mus rau kev cog qoob loo ntau tus kheej, lub luag haujlwm ntawm Parylene yuav nthuav dav. Peb pom zoo rau kev tshawb fawb rau hauv cov tshuaj tua kab mob Parylene kom txo qis kev pheej hmoo kis mob ntxiv. Cov neeg tsim khoom yuav tsum tshawb nrhiav kev sib xyaw Parylene nrog tshuaj - tshem tawm cov thev naus laus zis rau stents. Los ntawm nyob rau hauv pem hauv ntej ntawm cov kev tsim kho tshiab, kev lag luam tuaj yeem xa cov khoom siv uas tsis yog tsuas yog ua haujlwm xwb tab sis kuj tseem kho tau.