https://www.nature.com/articles/s41598-024-72620-8

Nrog rau kev loj hlob tsis tu ncua ntawm kev kuaj mob tsawg kawg nkaus thiab kev kho mob, nrog rau kev nce qib sai ntawm kev txawj ntse ntse thiab tshiabcov ntaub ntawv,radiopaque biopsy koob-ib zaug suav tias yog cov cuab yeej kho mob ib txwm muaj- tam sim no tau nkag mus rau nthwv dej tshiab ntawm kev tsim kho tshiab. Lub neej yav tom ntej ntawm cov koob no yuav dhau mus dhau qhov "visibility," hloov mus rau ntau dua kev txawj ntse, kev nyab xeeb, thiab kev ua haujlwm zoo.

1. Pushing the Limits of Visibility: Los ntawm "pom" mus rau "pom meej"

Thaum cov thev naus laus zis radiopacity tam sim no tau daws qhov teeb meem yooj yim ntawm kev pom, lawv qhov kev ua tau zoo tseem poob qis hauv cov ntaub so ntswg sib sib zog nqus, cov neeg mob rog, lossis thaj chaw uas muaj calcifications. Kev txhim kho yav tom ntej yuav tsom mus rau:

• Full -Ntev Radiopacity:Feem ntau cov koob uas twb muaj lawm muaj cov xov tooj cua tsuas yog nyob rau ntawm lub ntsis lossis hauv cheeb tsam. Cov txheej txheem txheej txheej siab tshaj plaws thiab micro- cov qauv tsim yuav ua kom tag nrho - ntev, 360-degree pom los ntawm lub taub hau mus rau lub hub, muab cov kws kho mob ua tiav, tsis muaj kev pom zoo rau tag nrho cov koob trajectory.
• Dynamic Radiopacity:Cov txheej txheem ntse teb rau cov lus qhia ib puag ncig ib puag ncig- xws li pH lossis qhov kub thiab txias - yuav raug tsim. Piv txwv li, thaum nkag mus rau acidic microenvironment ntawm cov qog, lub radiopacity tuaj yeem ua kom nrawm dua, lees paub meej lub hom phiaj hauv zos.
• Multimodal Imaging Compatibility:Kev sib xyaw ua ke ntawm ultrasound sib piv nrog CT / MRI compatibility. Los ntawm embedding tus nqi ntawm gadolinium los yog barium cim nyob rau hauv lub koob ncej, nws yuav pom nyob rau hauv ntau yam imaging modalities, ua kom yooj yim seamless kev koom ua ke ntawm preoperative npaj thiab intraoperative kev taw qhia.

2. Kev sib koom ua ke ua haujlwm: Los ntawm "Diagnostic Tool" mus rau "Therapeutic Platform"

Yav tom ntej radiopaque biopsy koob yuav hloov mus rau hauv ntau lub platforms.

• Integrated Sensing:Lub siab me me, qhov kub thiab txias, lossis cov khoom siv kho qhov muag uas muab tso rau ntawm rab koob yuav tso cai rau cov kws kho mob tsis yog pom xwb tab sis kuj "xav" - muab qhov tseeb - lub sij hawm tawm tswv yim txog kev hloov pauv, qhov kub thiab txias hauv cheeb tsam, los yog cov yam ntxwv spectral, pab txheeb xyuas qhov sib thooj rau cov hlab ntsha, paj hlwb, los yog cov qog nqaij hlav.
• Integrated Therapy:Kev sib xyaw cov koob radiopaque nrog cov xov tooj cua, microwave, laser, lossis cryoablation muaj peev xwm ua rau "koob{0}} raws li - kho." Xwb, microfluidic channels hauv rab koob tuaj yeem xa cov tshuaj kom meej, nqus cov kua dej, lossis sau cov ntaub so ntswg.
• Integrated Navigation:Seamless kev koom ua ke nrog electromagnetic los yog optical navigation systems tso cai rau sab nraud taug qab ntawm me me nyob rau hauv lub sensors, overlaying tiag - sij hawm koob txoj hauj lwm mus rau preoperative 3D reconstructions rau GPS-zoo li precision.

3. Kev txawj ntse thiab Automation: AI-Powed Precision Puncture

Artificial Intelligence (AI) yuav hloov pauv txoj kev puncture cov txheej txheem.

• AI-Assisted Recognition:AI algorithms tuaj yeem kuaj pom thiab piav qhia lub koob hauv cov duab ultrasound-txawm tias muaj suab nrov- thiab kwv yees nws txoj hauv kev kom raug.
• Intelligent Planning thiab ceeb toom:Cov kab ke yuav siv lub hom phiaj ua ntej thiab txoj hauv kev nyab xeeb los ua kom pom kev pom lossis hnov ​​​​cov lus ceeb toom thaum tus neeg teb xov tooj deviates los ntawm txoj kev npaj lossis thaum rab koob mus txog cov qauv tseem ceeb xws li cov hlab ntsha loj.
• Neeg hlau-Assisted Puncture:Cov neeg hlau sib koom ua ke tuaj yeem ua tiav cov koob txhaj tshuaj raws li cov tswv yim los ntawm tus kws kho mob los ntawm kev tswj lub console, tshem tawm tes tshee thiab ua tiav sub- millimeter raug.

4. Kev Lag Luam Kev Lag Luam: Ua raws li tus kheej thiab tus kheej

Cov kev cai nruj dua: Cov cai tswj hwm thoob ntiaj teb yuav tswj xyuas nruj dua ntawm Chav Kawm III cov cuab yeej kho mob, tshwj xeeb yog hais txog biocompatibility thiab cov ntaub ntawv kho mob tau zoo. Cov tuam txhab yuav tsum nce R & D peev thiab tsim kom muaj kev tswj hwm kev tswj hwm zoo uas npog tag nrho cov khoom lag luam lifecycle.

Kev Loj Hlob Ntawm Kev Kho Kom Zoo: Cov koob tshuaj radiopaque biopsy tus kheej tsim rau cov kab mob tsawg, cov neeg mob me, lossis cov qauv anatomical tshwj xeeb yuav tshwm sim . 3D tshuab luam ntawv tau npaj los ua lub luag haujlwm tseem ceeb hauv cheeb tsam no.

Kev sib koom ua ke ntawm Cov Khoom Siv Khoom Siv: Kev sib koom tes zoo dua ntawm cov khoom siv hluav taws xob sab saud (tshwj xeeb hlau, siab -cov khoom siv hluav taws xob), midstream manufacturers (precision machining, txheej thev naus laus zis), thiab cov neeg siv kho mob hauv qab yuav ua kom cov thev naus laus zis hloov pauv sai.

Hauv kev xaus, yav tom ntej ntawm radiopaque biopsy koob tuav tsis muaj peev xwm. Nws yuav hloov zuj zus los ntawm qhov tsis muaj zog "piercing tool" mus rau hauv lub davhlau ya nyob twg ntse integrating kev nkag siab, kev suav, kev sib txuas lus, thiab kev ua tiav, dhau los ua qhov tseeb "tag nrho- rounder" hauv kev phais me me.