Ntsiab lus: AVF puncture koob, chaw tsim tshuaj paus, soj ntsuam daim ntawv thov, tsim optimization, hemodynamics

Hauv kev kho hemodialysis, AVF puncture koob ua raws li qhov tseem ceeb ntawm kev sib txuas ntawm cov neeg mob cov hlab ntsha fistula thiab cov khoom siv lim dej loj. Nws qhov kev ua tau zoo cuam tshuam ncaj qha rau kev lim ntshav txaus, kev nplij siab ntawm tus neeg mob thiab lub sijhawm ntev -fistula kev pabcuam lub neej. Tsis yog ib rab koob yooj yim hollow steel, nws sawv cev rau kev ua tiav kev sib koom ua ke nrog cov tshuaj kho mob, dej mechanics thiab cov khoom siv engineering. Los ntawm hauv- kev sib koom tes tob nrog cov kws kho mob tshwj xeeb, cov kws tshaj lij kev lag luam txuas ntxiv txhim kho cov qauv tsim kom ua tiav lub hom phiaj tseem ceeb: xa cov ntshav rho tawm kom zoo thaum tiv thaiv cov peev txheej vascular mus rau qhov siab tshaj plaws.

1. Lub Hom Phiaj Tseem Ceeb: Siab- ua haujlwm tau zoo, ruaj khov thiab qis- puas tsuaj rau Ntshav Channel

Tsis pub dhau 4 mus rau 5 teev ntawm kev lim ntshav, AVF koob tsim ob txoj hauv kev ruaj khov uas kos 300 mus rau 450 milliliters ntawm cov ntshav ib feeb thiab rov qab cov ntshav ntshiab ntawm qhov sib npaug. Cov koob yuav tsum ua raws li cov cai hauv qab no:

Muaj peev xwm txaus txaus nrog rau sab hauv txoj kab uas hla thiab tsis tshua muaj raj phab ntsa tsis kam.

Zoo tshaj biocompatibility yam tsis muaj kev phiv tshwm sim thaum sib cuag ntshav.

Kev raug mob tsawg kawg nkaus ntawm cov lus qhia ntse thiab ua kom zoo dua geometry kom txo qis vascular phab ntsa laceration.

Kev kho kom ruaj khov kom tsis txhob muaj kev hloov pauv thiab kev nkag mus rau phab ntsa ntawm phab ntsa tom qab thaum kho.

Kev nyab xeeb ua haujlwm siab los tiv thaiv kev raug mob ntawm rab koob thiab kev phom sij rau ntshav.

2. Tswv yim tsim: Sib npaug ntawm Puncture Experience thiab Tissue Protection

Raws li thawj feem cuam tshuam rau tib neeg cov ntaub so ntswg, koob tip design yog qhov tseem ceeb heev.

• Bevel qauv thiab puncture force: Multi-bevel designs xws li triple-bevel tswv yim xyuas kom meej kom qis puncture kuj thiab txhim khu rigidity tiv thaiv dabtsi yog khoov. Txo puncture quab yuam alleviates tus neeg mob mob thiab blunt vascular puas.
• mem hluav- taw tes thiab rov qab bevel tsim: Sib txawv ntawm cov qauv txiav bevels, cov cwj mem tshiab tshiab - cov lus qhia zoo li maj mam cais cov ntaub so ntswg es tsis txhob txiav lawv, theoretically txo qis vascular raug mob thiab ua kom lub sijhawm kho tom qab lub sijhawm luv.

3. Side Hole Innovation: Hemodynamic Evolution los ntawm Ib Lub Qhov Rau Ntau - qhov qauv

Ib txwm AVF koob tsuas muaj ib lub davhlau ya nyob twg qhib, uas yooj yim ua rau ntau yam tsis zoo nyob rau hauv siab - ntws nqus.

• Phab ntsa adhesion nyhuv: Cov phab ntsa vascular tuaj yeem txuas rau thiab thaiv qhov kawg ntawm qhov kawg, cuam tshuam cov ntshav ntws thiab ua rau lub tswb nrov. Cov kws saib xyuas neeg mob yuav tsum tau kho cov koob tshuaj ntau zaus, cuam tshuam kev kho mob thiab ua rau cov ntaub so ntswg puas.
• Siab shear quab yuam thiab turbulence: Concentrated inflow generates khaus shear force thiab turbulent flow, uas yuav ua rau hemolysis thiab platelet activation.
• Tsis sib xws khiav ceev: Muaj zog nqus ncaj qha ua ntej ntawm lub taub hau yuav ua rau cov hlab ntsha hauv zos intima.
• Cov qauv sab hauv yog tsim los daws cov teeb meem saum toj no thiab tau dhau los ua lub cim ntawm siab -kawg AVF koob. Ib los yog ntau lub qhov yog raug tsim los ntawm lub raj nyob ze ntawm qhov kawg ntawm tsib -axis laser machining.

Dispersed suction cov ntsiab lus tiv thaiv lub nkoj phab ntsa thaiv ntawm ib qho qhib.

Txo cov dej ntws hauv zos thiab lub zog shear zoo txo ​​cov ntshav cell puas tsuaj nyob rau hauv qhov ntim tas li.

Ntau- qhov nkag hauv cov ntaub ntawv tsis tu ncua laminar ntws thiab tswj cov ntshav rho tawm kom ruaj khov.

Reserve siab guarantee ua kom tsis muaj kev cuam tshuam cov ntshav txawm tias qhov kawg qhov ua raws li cov phab ntsa ntawm cov hlab ntsha, txhim kho kev kho mob thiab kev ua txhaum cai.

4. Koob Tube tsim thiab kho: Kev lees paub ntawm kev ua haujlwm ruaj khov

• Sib npaug ntawm rigidity thiab yooj: Kev kho lub raj kom zoo thiab kev kho cua sov tiv thaiv kev khoov thaum lub sij hawm puncture thiab fixation, thiab tsis txhob lever - hom kev raug mob tshwm sim los ntawm kev nruj heev thaum cov neeg mob txav mus.
• tis thiab kho accessories: Cov tis dav dav txhawb kev tuav ruaj khov thiab qhov chaw. Pab kho cov tis, cov ntaub nplaum nplaum thiab cov khoom sib txuas sib txuas kom ruaj ntseg cov koob kom nruj thiab tiv thaiv kev slippage. Kev ruaj ntseg clips kaw cov lus qhia ntse tam sim tom qab rab koob tshem tawm kom tsis txhob raug mob.
• Ntev thiab cim: Koob raj nrog tus qauv ntev nyob ib ncig ntawm 25 hli hloov mus rau qhov sib txawv ntawm cov rog subcutaneous. Cov cim qhia ntev thiab cov kab qhov tob tob pab cov neeg ua haujlwm kho mob tswj qhov tob tob kom raug thiab zam kev nkag mus rau vascular tom qab.

5. Kev sib cuam tshuam ntawm cov chaw tsim khoom thiab chaw kho mob: Kev tsim kho tshiab los ntawm kev xav tau

Cov tuam txhab ua lag luam tsim cov chaw kho mob tshwj xeeb, nrog rau kev tshawb fawb thiab kev tsim kho los ntawm cov tswv yim kho mob tiag tiag.

• Pain point collection: Kev sib txuas lus tsis tu ncua nrog cov kws saib xyuas neeg mob lim ntshav thiab cov kws kho mob nephrologists sib sau cov teeb meem xws li cov hlab ntsha dov, cov ntshav tsis ruaj khov thiab nyuaj hemostasis tom qab txhaj koob.
• Tswv yim tsim: Engineers hloov kho qhov xav tau rau hauv kev daws teeb meem. Cov teeb meem tsis ruaj khov ua rau muaj ntau- sab qhov tsim, thaum qhov yuav tsum tau kho mob ua rau kev ua kom zoo ntawm geometric ntawm qis- cov lus qhia tiv thaiv.
• Kev sim qauv: Fluid dynamics thwmsim ntsuas tus nqi ntws, siab poob thiab hemolysis indicators. Simulated cov ntaub so ntswg puncture tests thiab xam cov kua dej dynamics simulation ntxiv optimize flow field kev ua tau zoo.
• Kev kuaj xyuas: Pilot soj ntsuam kev sim sau cov ntaub ntawv siv tau nrog rau qhov ua tau zoo ntawm kev sib tsoo, qhov mob tau thiab cov ntshav ntws ruaj khov.

Xaus

Niaj hnub nimno AVF puncture koob tsim yog ib tug neeg mob -qhov tseem ceeb systematic project tsom rau kev tiv thaiv vascular. Txhua qhov kev ua kom zoo, los ntawm qhov mob-txo cov lus qhia thiab ntws tawm- txhim kho sab qhov rau kev nyab xeeb kho cov cuab yeej, embodies cov kev pom zoo hauv kev kho mob thiab cov cuab yeej thev naus laus zis. Cov neeg tsim khoom tau hloov zuj zus los ntawm cov khoom lag luam passive mus rau cov kws kho mob cov teeb meem daws teeb meem thiab cov koom tes tsim kho tshiab. Kev ua kom zoo tsis tu ncua ntawm qhov tseem ceeb ntawm lub neej cuam tshuam no txhim kho ib zaug - kev lim ntshav zoo thiab txhawb nqa ntev - lub sijhawm patency ntawm arteriovenous fistulas, lub neej tsis hloov pauv ntawm cov neeg mob lim ntshav.