Comprehensive Quality Control Thiab Traceability System

Kev tswj hwm zoo ntawm Chiba koob khiav los ntawm tag nrho cov txheej txheem tsim khoom, thiab muaj cov qauv nruj thiab kev sim ntawm txhua theem.
Kev tshuaj xyuas qhov loj me siv ntau- thev naus laus zis kev sib koom ua ke. Sab nraud txoj kab uas hla thiab phab ntsa thickness yog ntsuas siv lub laser txoj kab uas hla gauge nrog ib tug raug ntawm ± 0.001mm, thiab 100% tag nrho kev soj ntsuam yog ua. Sab hauv txoj kab uas hla yog ntsuas siv lub ntsuas cua piston nrog qhov tseeb ntawm ± 0.002mm. Qhov ntev yog ntsuas siv qhov projector optical nrog qhov tseeb ntawm ± 0.01mm. Lub taub geometry yog ntsuas siv peb -dimensional profilometer nrog kev daws teeb meem ntawm 0.1μm.
Mechanical Performance tests simulate kev siv tiag tiag. Qhov kev ntsuas quab yuam siv tus qauv gelatin (kev sib xyaw 10%, kub 37 degree), nrog rau qhov nrawm ntawm 10mm / s, ntsuas qhov siab tshaj plaws thiab nruab nrab puncture rog. Txoj kev khoov khov kho siv peb txoj hauv kev- taw tes dabtsi yog khoov, nrog rau qhov ntev ntawm 20mm thiab qhov ceev ntawm 1mm / min, los ntsuas qhov elastic modulus. Kev ntsuas lub zog torsional siv lub zog kom txog thaum tsis ua haujlwm, nrog 22G koob muaj qhov tsawg kawg nkaus torque ntawm 0.05N·m.
Kev txheeb xyuas kev ua haujlwm ua haujlwm kom ntseeg tau tias kev kho mob tau zoo. Flow tests ntsuas qhov nqus thiab txhaj tshuaj muaj peev xwm: ntawm qhov tsis zoo siab ntawm 0.1 MPa, nws yuav siv sijhawm tsis tshaj 3 vib nas this los nqus 5 mL dej; ntawm qhov zoo siab ntawm 0.1 MPa, nws yuav siv sij hawm tsis pub tshaj 2 vib nas this los txhaj 5 mL dej. Sealing xeem tswj lub siab rau 30 vib nas this ntawm 0.3 MPa yam tsis muaj dej. Lug sib koom ua ke ua raws li ISO 80369 tus qauv; Kev sib txuas quab yuam yog 5-15 N, thiab kev sib hloov torque yog 0.1-0.3 Nm.
Kev kuaj biocompatibility ua raws ISO 10993. Kev kuaj cytotoxicity siv MTT txoj kev. Cov tshuaj extract yog npaj ntawm ib tug concentration ntawm 3 cm² / mL, thiab sab laug rau tsau ntawm 37℃rau 72 teev. Tus naj npawb ntawm cov ciaj sia taus yog ntau dua lossis sib npaug li 80%. Qhov kev ntsuam xyuas rhiab heev tau txais txoj kev siab tshaj plaws, thiab cov tshuaj tiv thaiv ntawm daim tawv nqaij ntawm guinea npua yog tsawg dua los yog sib npaug rau me me erythema. Kev kuaj genotoxicity yog ua los ntawm Ames kuaj thiab kuaj chromosome aberration.
Cov txheej txheem traceability ua kom tag nrho - kev soj ntsuam cov txheej txheem. Txhua rab koob muaj tus lej cim tshwj xeeb, uas sau cov batch ntawm raw cov ntaub ntawv, kev ua tsis tau, xeem cov ntaub ntawv, thiab cov neeg ua haujlwm. Los ntawm MES system, txhua qhov teeb meem zoo tuaj yeem taug qab mus rau cov txheej txheem tshwj xeeb thiab tus neeg saib xyuas. Lub sijhawm khaws cov ntaub ntawv yog tsawg kawg yog 10 xyoo, ua tau raws li FDA 21 CFR Part 820.
Intelligent Manufacturing thiab Future Trends
Kev tsim cov koob Chiba yog txav mus rau qhov kev txawj ntse thiab cov kev taw qhia digital. Cov cuab yeej digital ntxaib tsim cov qauv tsim virtual, simulates cov txheej txheem ua haujlwm, ua kom cov txheej txheem tsis zoo, thiab ua kom lub voj voog luv luv ntawm 2 lub lis piam mus rau 2 hnub. Artificial txawj ntse soj ntsuam cov ntaub ntawv tsim khoom, kwv yees cov qauv zoo, thiab kho qhov ntsuas ua ntej, txo qhov tsis xws luag ntawm 500 ppm rau 50 ppm.
Cov kab ntau lawm automated txhim khu kev sib xws. Robots tswj kev thauj khoom thiab tshem tawm, tshuaj xyuas, thiab ntim khoom, txo kev cuam tshuam tib neeg los ntawm 80%. Lub qhov muag pom tau txais kev txheeb xyuas qhov tsis xws nrog qhov tseeb ntawm 99.9%. Kev tswj hwm kev hloov pauv hloov cov txheej txheem ua haujlwm hauv lub sijhawm tiag tiag kom them nyiaj rau cov cuab yeej hnav thiab kub hloov pauv.
Kev kho tus kheej raws li kev xav tau tshwj xeeb. Raws li tus neeg mob cov ntaub ntawv CT, 3D luam ntawv yog siv los tsim cov koob ntawm tus kheej, ua kom lub koob lub kaum ntse ntse thiab curvature rau cov qauv anatomical tshwj xeeb. Cov khoom me me -batch hloov pauv tau txais yuav, nrog rau qhov tsawg kawg nkaus txiav txim kom muaj nuj nqis txo los ntawm 1,000 mus rau 100, thiab lub sijhawm xa khoom luv luv ntawm 4 lub lis piam mus rau 1 lub lis piam.
Green manufacturing txo kev cuam tshuam ib puag ncig. Dej- cov tshuaj ntxuav tu raws li cov kuab tshuaj organic, nrog cov dej khib nyiab rov siv dua 90%. Txiav qhuav txo qhov kev siv cov coolant. Kev siv cov khoom siv tau nce los ntawm 60% mus rau 85%. Ntim siv cov ntaub ntawv degradable, nrog cov pa roj carbon hneev taw txo 40%.
Kev tsim cov koob Chiba yog ib qho kev kos duab ntawm precision engineering, thiab nws kuj yog kev hwm rau lub neej. Los ntawm cov khoom siv raw mus rau cov khoom tiav, txhua kauj ruam suav nrog cov khoom siv tes ua haujlwm thiab lub luag haujlwm ntawm cov tuam ntxhab. Nyob rau hauv lub ntiaj teb no nrog ib txoj kab uas hla ntawm tsawg tshaj li 1 millimeters, precision txiav txim siab cov nyhuv, thiab zoo kev txhawj xeeb txog lub neej. Tsuas yog cov tuam txhab lag luam uas paub txog cov txheej txheem tseem ceeb, ua raws li cov qauv siab tshaj plaws, thiab tsis tu ncua innovate thiab iterate tuaj yeem muab cov cuab yeej txhim khu kev qha rau cov tshuaj precision, pab cov kws kho mob tsim cov txuj ci tseem ceeb ntawm lub neej hauv lub ntiaj teb microscopic.
Clinical Application Progress thiab Technological Innovation ntawm Chiba Koob
Txij li thaum nws txoj kev loj hlob los ntawm Lub Tsev Haujlwm Saib Xyuas Tshuaj ntawm Chiba University hauv Nyij Pooj xyoo 1970, Chiba Needle tau hloov zuj zus los ntawm cov cuab yeej biliary puncture yooj yim mus rau qhov tseem ceeb ntawm ntau yam -cov cuab yeej ua haujlwm hauv thaj chaw ntawm kev cuam tshuam hluav taws xob. Nyob rau niaj hnub no txoj kev loj hlob sai nyob rau hauv kev yees duab kev taw qhia technology, daim ntawv thov Scope ntawm lub Chiba koob yog tas li nthuav, thiab technologies innovation yog tas li tshwm sim, uas yog redefining ciam teb ntawm minimally invasive kuaj mob thiab kev kho mob.
Percutaneous biopsy: Los ntawm cov ntaub so ntswg mus rau kev kuaj mob molecular
Percutaneous biopsy yog daim ntawv thov classic tshaj ntawm Chiba koob. Txawm li cas los xij, niaj hnub biopsy yog ntau dua li tau txais cov ntaub so ntswg. Hauv CT- coj lub ntsws nodule biopsy, qhov tseeb ntawm 22G Chiba koob (sab nraud txoj kab uas hla 0.7mm) yog 92-95%, qhov tshwm sim ntawm pneumothorax yog 12-15%, thiab qhov tshwm sim los ntshav yog 5-8%. Tab sis kev kuaj mob histological yooj yim ib leeg tsis tuaj yeem ua tau raws li qhov xav tau ntawm cov tshuaj precision.
Cov txheej txheem coaxial tau nce biopsy mus rau qib tshiab. Ib 19G guiding koob (sab nraud txoj kab uas hla 1.0mm) tsim ib channel, thiab 22G biopsy koob siv ntau yam qauv los ntawm coaxial sheath, tau txais 3-5 cov ntaub so ntswg strips, txhua 1.5-2.0cm nyob rau hauv ntev. Cov txheej txheem no nce qhov kev kuaj mob mus rau 97%, thaum txo tus naj npawb ntawm pleural punctures thiab txo qis pneumothorax tus nqi mus rau 8%. Dab tsi yog qhov zoo tshaj plaws yog cov txheej txheem tandem, qhov twg ob rab koob yog punctured ib txhij, nrog rau ib rab koob siv rau biopsy thiab lwm yam rau kev kos, muab qhov tseeb qhov chaw rau kev phais tom ntej los yog ablations.
Molecular biopsy opens up new horizons. The tissues obtained through the Kashima needle are not only used for pathological diagnosis but also for genetic testing. In lung cancer biopsy, the obtained tissues must meet the requirements of next-generation sequencing (NGS): the content of tumor cells should be >20%, the total amount of DNA should be >50ng, and the fragment length should be >200 ib. Qhov nruab nrab qhov hnyav ntawm cov ntaub so ntswg tau txais los ntawm 22G koob yog 15mg, thiab cov txiaj ntsig DNA yog 30-50ng / mg, uas txaus rau kev kuaj vaj huam sib luag ntawm 50-100 noob. Qhov no ua rau tus kheej lub hom phiaj kho tau. Qhov tseeb ntawm EGFR kev hloov pauv kom pom yog 95%, coj kev siv cov tshuaj tsom xws li gefitinib.
Ua kua biopsy yog ua ke nrog cov ntaub so ntswg biopsy. Thaum lub sij hawm puncture, 3-5 mL ntawm ib txwm saline yog txhaj los ntawm Kashima koob, thiab "txoj kua" yog retrieve los ntawm aspiration mus kuaj circulating qog DNA (ctDNA). Txoj kev tshawb no qhia tau hais tias qhov concentration ntawm ctDNA nyob rau hauv cov kua puncture yog 100-1000 npaug ntawm cov ntshav peripheral, thiab qhov kuaj pom tus nqi ntawm EGFR hloov pauv nce los ntawm 70% hauv cov ntshav mus rau 95%. Hom "ib-needle dual-test" hom no ua kom pom cov ntaub ntawv kuaj mob ntau tshaj plaws thiab tshwj xeeb tshaj yog tsim nyog rau cov neeg mob uas muaj cov qog nqaij hlav tsawg.
Percutaneous puncture drainage: Los ntawm cov kua dej yooj yim mus rau kev tswj xyuas
Daim ntawv thov ntawm Chiba koob nyob rau hauv lub tshav pob ntawm cov kua dej tau hloov zuj zus los ntawm yooj yim cyst aspiration mus rau complex kua ntawm abscesses, hematomas, thiab kua tsib. Raws li kev taw qhia ultrasound, lub siab cyst puncture yog ua los ntawm 18G Chiba koob (sab nraud txoj kab uas hla 1.2 hli) los nqus cov kua dej, thiab cov tshuaj sclerosing (xws li anhydrous ethanol) raug txhaj rau kev kho mob. Tus nqi kho yog 85-90%, thiab tus nqi rov qab yog 10-15%. Txawm li cas los xij, cov dej ntws niaj hnub no tseem ceeb dua rau tag nrho cov txheej txheem kev tswj hwm.
Cov txheej txheem ntawm pancreatic pseudocyst kua dej tau pom muaj kev vam meej. Siv 19G Chiba koob nyob rau hauv CT kev taw qhia txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau 8-10F lub raj xa dej los ntawm cov txheej txheem Seldinger. Txawm li cas los xij, qhov rov tshwm sim ntawm cov kua dej yooj yim yog 20-30%. Tam sim no, ua ke nrog kev tso chaw endoscopic ntawm stent los ntawm lub plab lossis duodenum, tsim kom muaj lub cyst-kab mob plab hauv plab, qhov kev kho mob ntev tau nce mus rau 90%. Dab tsi yog qhov tshiab tshaj plaws yog ultrasound endoscopy-guided puncture, ncaj qha nkag mus rau hauv lub cyst los ntawm lub plab phab ntsa, nrog tsawg dua kev raug mob thiab txo qis kev pheej hmoo kis mob.
Technological innovation nyob rau hauv daim siab abscess kua. Yav dhau los, 12-14F tuab raj tau siv rau cov kua dej, tab sis nws ua rau cov neeg mob tsis xis nyob. Tam sim no, ib rab koob 8.5F Kashima yog siv rau kev sib tsoo, thiab 8F multi-lub qhov dej raj tau muab tso rau. Ua ke nrog cov dej hauv mem tes (siv 20mL ntawm ib txwm saline rau kev txhaj tshuaj sai thiab yaug txhua 4 teev), cov kua dej ua haujlwm tau nce 30%. Rau ntau lub ntsej muag abscesses, ib rab koob Kashima (nrog rau 30℃khoov lub taub hau) yog siv los txhawm rau txhua qhov chaw ib los ntawm ib qho, nce qhov kev vam meej ntawm 60% mus rau 85%.
Cov evolution ntawm biliary kua cov txheej txheem. Percutaneous transhepatic cholangial drainage (PTCD) yog daim ntawv thov classic ntawm Chiba koob, tab sis cov txheej txheem ib txwm xav tau ntau yam punctures thiab muaj qhov teeb meem loj. Tam sim no, nrog kev siv ultrasound thiab fluoroscopy rau kev taw qhia dual, 21G Chiba koob yog siv rau kev sib tsoo. Thaum cov kua tsib ntws tawm, tus neeg sawv cev sib txawv tau txhaj tshuaj kom paub meej txog qhov biliary anatomy, thiab tom qab ntawd muab lub raj xa dej tso. Cov txheej txheem txhim kho no tau nce qhov kev vam meej ntawm ib qho kev sib tsoo los ntawm 70% mus rau 90%, thiab cov ntshav los ntshav tau txo qis los ntawm 8% mus rau 3%. Rau cov kab mob biliary obstruction ntawm lub hepatic hilum, cov txheej txheem coaxial yog siv los ntxig ntau lub raj xa dej kom ntws cov hlab ntsha sab laug thiab sab xis nyias nyias. Tus kab mob jaundice regression tau nce los ntawm 65% mus rau 85%.
Vascular Intervention: Los ntawm Txoj Kev Tsim Kho mus rau Kev Ua Haujlwm Zoo
Kailian koob ua lub luag haujlwm ntawm "qhov rooj qhib" hauv kev cuam tshuam ntawm vascular, tab sis nws cov kev siv niaj hnub mus deb tshaj qhov yooj yim puncture. Hauv transjugular intrahepatic portosystemic shunt (TIPS) cov txheej txheem, Kailian koob yog siv los txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau txhawm Siv 16G Kailian rab koob (sab nraud txoj kab uas hla 1.6mm) nyob rau hauv kev taw qhia ultrasound rau puncture, ua ke nrog portal vein angiography, qhov ua tau zoo yog 95-98%. Txawm li cas los xij, cov txheej txheem ib txwm muaj kev raug mob siab ntawm cov hlab ntsha ntawm 3-5%, thaum tam sim no nrog kev qhia ntawm ultrasound ntawm lub sijhawm tiag tiag thiab zam cov ceg ntawm cov hlab ntshav siab, qhov raug mob tau poob qis dua 1%.
Technological kev nce qib hauv kev tsim kom muaj kev nkag mus rau kev lim ntshav. Rau cov neeg mob uas muaj cov hlab ntsha tsis zoo, kev siv cov khoom siv micro- puncture yog pom zoo: 21G Chiba koob puncture, 0.018-inch guidewire insertion, thiab maj mam dilation mus rau 6F sheath. Cov txheej txheem micro-txoj kev no txo ​​qis qhov tshwm sim ntawm hematoma ntawm 15% mus rau 3%, thiab tshwj xeeb tshaj yog haum rau cov neeg mob rog. Dab tsi yog qhov zoo tshaj plaws yog ultrasound fusion thev naus laus zis, uas ua ke nrog CT vascular imaging nrog ultrasound real-time kom pom cov kab mob vascular, thiab qhov kev ua tiav ntawm kev sib tsoo yog ze rau 100%.
Cov ntawv thov tshiab hauv Tumor Embolization. Nyob rau hauv transarterial chemoembolization (TACE) rau hepatocellular carcinoma, Kashima koob yog siv rau punctureing cov hlab ntsha femoral, tab sis niaj hnub cov tswv yim yog ntau refined. A 4F microcatheter yog siv rau super- xaiv ntxig rau hauv cov qog- pub cov hlab ntsha, thiab cov tshuaj- loaded microspheres (inch 100-}300 μm) yog txhaj los ntawm Kashima koob, ua rau kom ntau dua embolization nrog kev puas tsuaj rau daim siab li qub. Ua ke nrog CT-guided radiofrequency ablation, 3-xyoo txoj sia nyob tau nce los ntawm 50% mus rau 70%.
Sclerotherapy rau varicose leeg. Under ultrasound guidance, a Chiba needle is used to puncture the varicose veins and inject foam sclerosing agent (polydocanol mixed with air in a 1:4 ratio). Lub multi-sab koob lub tswv yim tsim kom ntseeg tau tias muaj kev faib tawm ntau dua ntawm tus neeg sawv cev sclerosing, txo qhov rov tshwm sim ntawm 30% mus rau 15%. Rau qhov zoo saphenous varicose leeg, ib lub laser fiber ntau yog siv los nkag rau hauv cov hlab ntsha los ntawm Chiba koob rau intracavitary laser kaw. Qhov kev vam meej yog 98%, thiab lub sij hawm rov qab tau luv los ntawm 2 lub lis piam mus rau 3 hnub.
Kev kho mob: Los ntawm cov hlab ntsha thaiv mus rau intervertebral disc kho
Daim ntawv thov ntawm Kailian koob hauv kev kho mob tau dhau los ua qhov dav, nrog cov kev xav tau siab heev. Rau kev kho mob ntawm post-zoster neuralgia nrog paravertebral hlab ntsha thaiv, 25G Kailian koob (sab nraud txoj kab uas hla 0.5mm) tau muab tso rau hauv qhov chaw paravertebral raws li CT kev taw qhia thiab tshuaj loog hauv zos thiab cov tshuaj hormones raug txhaj. Cov txheej txheem ib txwm cia siab rau cov cim ntawm pob txha, nrog rau qhov ua tiav ntawm 80%, thaum txoj kev tam sim no siv peb - qhov loj me CT rov tsim kho kom pom cov koob tip txoj hauj lwm nyob rau lub sij hawm, nce qhov kev vam meej mus rau 95%.
Intervertebral disc imaging thiab kev kho mob. Using a 22G Chiba needle to puncture the intervertebral disc and inject contrast agent to assess the integrity of the annulus fibrosus, diagnosing discogenic pain. Dab tsi yog qhov tshiab tshaj plaws yog qhov intradiscal electrothermal therapy (IDET), qhov twg lub tshav kub - txias catheter yog ntxig los ntawm Chiba koob, rhuab mus rau 90℃rau 5 feeb, ua rau lub contraction ntawm collagen fibers thiab sealing lub tsim kua muag site. Qhov mob nyem yog 70-80%.
Radiofrequency ablation ntawm trigeminal ganglion. Using a 22G Chiba needle to puncture through the foramen ovale to the trigeminal ganglion, with the needle tip exposed for 5mm. Radiofrequency yog siv rau cua sov rau 70℃rau 90 vib nas this los kho trigeminal neuralgia. Cov txheej txheem ib txwm cia siab rau X-ray fluoroscopy, thaum tam sim no nws tau coj los ntawm CT, uas tuaj yeem qhia meej txog kev sib raug zoo ntawm rab koob thiab pob txha taub hau, tsis txhob puncture ntawm lub qhov ntswg. Qhov tshwm sim ntawm cov teeb meem loj tau txo los ntawm 2% mus rau 0.5%.
Kev sib koom tes kev kho mob. For shoulder joint imaging, a 22G Chiba needle is used to puncture the joint cavity and inject contrast agent to assess rotator cuff injuries. Kev kho mob ntau dua yog qhov puncture thiab irrigation ntawm calcific tendinitis, qhov twg ib rab koob 18G yog siv rau puncture calcified lesion, txhaj ib txwm saline rau irrigation, thiab tshem tawm cov calcified tshuaj. Qhov mob nyem yog 85%. Ultrasound kev taw qhia ua rau cov puncture ntau meej, nce qhov kev vam meej ntawm 75% mus rau 95%.
Tumor ablation: Los ntawm thermal ablation mus rau irreversible electroporation
Lub koob Chiba tsis tsuas yog ua haujlwm raws li cov cuab yeej xuas nrig xwb tab sis kuj ua raws li lub zog xa hluav taws xob hauv cov qog ablation. Rau kev kho mob qog noj ntshav me me siv xov tooj cua ablation, 17G Chiba koob (nrog rau txoj kab uas hla ntawm 1.4mm) nruab nrog cov electrodes sab hauv yog siv. Lub taub hau yog nthuav mus rau hauv ntau lub sub- koob, tsim ib qho chaw ablation nrog ib txoj kab uas hla ntawm 3-5cm. Txawm li cas los xij, ib txwm siv xov tooj cua ablation yog cuam tshuam los ntawm cov ntshav ntws los ntawm tshav kub dissipation. Tam sim no, bipolar radiofrequency tau saws, nrog ob rab koob Chiba ib txhij punncturing ob qhov kawg ntawm cov qog, ua rau ntau yam ablation thiab ib cheeb tsam rov tshwm sim ntawm 15% mus rau 8%.
Ua ntej hauv microwave ablation technology. Siv 14G Kashima koob nrog tsim-hauv microwave kav hlau txais xov, ntawm qhov zaus ntawm 2450 MHz, nrog lub zog ntawm 60-100W, thiab lub sijhawm ntawm 5-10 feeb, thaj tsam ablation nce mus txog qhov kub ntawm 60-100 degree. Microwave ablation tsis cuam tshuam los ntawm cov ntaub so ntswg carbonization, thiab thaj chaw ablation loj dua thiab tsis tu ncua. Rau cov mob qog noj ntshav loj (＞5cm), ntau koob synchronous ablation tau txais yuav, nrog 3-5 Kashima koob ua haujlwm ib txhij, nce qhov ua tiav ablation ntawm 60% mus rau 85%.
Kev siv tshiab ntawm irreversible electroporation (nanoknife). Siv 19G Chiba koob electrode, puncture cov qog nyob rau hauv ultrasound los yog CT kev taw qhia, nrog rau ib rab koob sib nrug ntawm 1.5-2.0 cm, thov siab -voltage hluav taws xob pulses (1500V / cm, 70-90 pulses) ua rau nanoscale perforations nyob rau hauv lub cell cell thiab insufficiency. Qhov no tsis yog-kub ablation khaws cov vascular thiab biliary qauv, haum rau cov qog ntawm lub siab hepatic thiab txo cov biliary stenosis ntawm 30% mus rau 5%.
Precise tswj ntawm cryoablation. Siv 17G Chiba koob nrog cov kua nitrogen hauv cov channel, qhov kub ntawm lub taub yog txo mus rau -160 degree, tsim ib lub pob dej khov kom tshem tawm cov qog. Kev kuaj xyuas lub sijhawm tiag tiag ntawm lub pob dej khov yog ua haujlwm kom tsis txhob muaj kev puas tsuaj rau cov ntaub so ntswg ib puag ncig. Rau cov qog nqaij hlav hauv lub raum, kev tiv thaiv lub raum ua haujlwm los ntawm cryoablation yog qhov zoo tshaj rau kev phais phais, nrog qhov txo qis hauv glomerular pom tus nqi tsuas yog 10% (piv rau 30% rau kev phais phais).
Yav tom ntej Outlook: Cov koob ntse ntse thiab kev taw qhia meej
Lub neej yav tom ntej ntawm Chiba koob nyob rau hauv kev txawj ntse thiab precision. Optical fiber sensing koob integrate optical fiber Bragg gratings, uas tuaj yeem ntsuas qhov hardness, kub thiab siab ntawm cov ntaub so ntswg nyob rau lub sijhawm, paub qhov txawv ntawm cov qog thiab cov ntaub so ntswg, nrog qhov tseeb ntawm 95%. Lub impedance sensing koob ntsuas qhov hluav taws xob tsis kam ntawm cov ntaub so ntswg, txheeb xyuas cov ntaub so ntswg, thiab qhov txawv ntawm cov khoom nodules thiab atelectasis hauv lub ntsws biopsies, nrog qhov tseeb ntawm 90%.
Sib nqus resonance tau tshaj koob qhib lub qab ntug tshiab. Ua los ntawm npib tsib xee-titanium alloy lossis carbon fiber, lawv tsim cov khoom siv tsawg tsawg hauv qab 3T MRI thiab tso cai rau- sijhawm saib xyuas cov txheej txheem ablation. Laser-induced thermotherapy (LITT) siv lub laser fiber ntau qhia los ntawm rab koob. Tiag -lub sij hawm ntsuas kub los ntawm MRI precisely tswj cheeb tsam ablation, nrog ib tug ntug yuam kev ntawm tsawg tshaj li 2 hli.
Robot-pab puncture txhim kho qhov tseeb. Lub caj npab neeg hlau tuav lub lancet koob thiab coj los ntawm CT lossis MRI, ua tiav qhov tseeb ntawm 0.5mm. Nws yog tshwj xeeb tshaj yog haum rau qhov tob me me (tsawg dua 1cm). Artificial txawj ntse npaj txoj kev puncture, zam cov hlab ntsha thiab cov qauv tseem ceeb, thiab txo cov teeb meem los ntawm 50%.
Lub rotatable koob lub taub hau txhim kho yooj. Lub taub hau tuaj yeem ua haujlwm los yog thermally qhib kom khoov, nrog lub kaum sab xis siab tshaj plaws ntawm 30 degree, ua kom nkhaus ntswj thiab hla cov teeb meem. Nws yog siv rau kev kuaj mob qog nqaij hlav prostate, npog thaj chaw uas cov tsoos ncaj nraim tsis tuaj yeem ncav cuag, thiab qhov kev kuaj mob qog noj ntshav nce 20%.
Cov koob xa tshuaj siv tshuaj kho mob hauv zos. Qhov ntau- qhov tsim ntawm lub taub hau kom ntseeg tau tias muaj kev faib tawm ntau dua ntawm cov tshuaj. Cov kev txhawb nqa - tso tawm txheej khaws cov tshuaj tua kab mob hauv cov koob channel thiab tso tawm tsis tu ncua rau 7-14 hnub. Cov tshuaj hauv zos concentration yog 100 npaug ntawm kev tswj hwm cov hlab ntsha, thiab cov kab mob toxicity raug txo los ntawm 80%.
Kev txhim kho keeb kwm ntawm Chiba koob yog microcosm ntawm kev cuam tshuam hluav taws xob: los ntawm kev yooj yim mus rau qhov nyuaj, los ntawm kev kuaj mob mus rau kev kho mob, los ntawm qhov tsis paub txog qhov tseeb. Txhua qhov kev tsim kho thev naus laus zis tau nthuav dav daim ntawv thov, thiab txhua txoj kev txhim kho tau txhim kho kev nyab xeeb. Nyob rau hauv lub neej yav tom ntej, nrog rau kev koom ua ke ntawm cov ntaub ntawv science, imaging technology, thiab txawj ntse txawj ntse, lub Chiba koob yuav mus txuas ntxiv mus, noj nyob rau hauv ib tug ntau ntse, meej dua, thiab muaj kev ruaj ntseg daim ntawv, thiab sau ib tug tshiab tshooj nyob rau hauv lub ntiaj teb no loj heev ntawm cov tshuaj minimally invasive.