Tshaj Tawm Puncture: Yav Tom Ntej Trends Ntawm Daim Siab Biopsy Techniques Thiab Txoj Kev Tsim Kho Tshiab Ntawm Cov Khoom Siv Hluav Taws Xob Cov Hluav Taws Xob

Txawm hais tias percutaneous daim siab biopsy sawv cev los ntawm koob Menghini tseem yog "tus qauv kub" rau kev kuaj mob, kev nce qib ntawm cov tshuaj yeej tsis nyob twj ywm. Cov neeg mob lub siab xav kom tsis yog -invasive/micro-kev kuaj mob, qhov kev thov rau cov ntaub ntawv piv txwv ntau dua hauv cov tshuaj precision, thiab kev nce qib hauv kev siv hluav taws xob hluav taws xob yog txhua yam ua rau kev hloov pauv ntawm kab mob siab rau kev kuaj mob rau qhov tseeb dua, kev nyab xeeb dua, thiab cov ntaub ntawv muaj txiaj ntsig zoo dua. Rau cov tuam txhab lag luam ntawm cov cuab yeej phais mob me me raws li cov koob Menghini, kev nkag siab txog cov qauv no thiab kev npaj ua ntej yog cov yuam sij kom ntseeg tau tias lawv tsis raug tshem tawm los ntawm lub sijhawm thiab txawm tias coj mus rau lwm qhov kev tsim kho tshiab.
Txoj Kev 1: Kev sib sib zog nqus ntawm cov duab taw qhia thiab kev yees duab navigation. Yav tom ntej daim siab biopsies yuav tsis yog "dig muag punctures" lossis tsuas yog ob - qhov chaw ntawm qhov chaw ultrasound. Tiag -lub sij hawm peb-dimensional ultrasound fusion imaging, CT/MRI foundations navigation, thiab lwm yam., tuaj yeem ua ke ua ntej ua haujlwm siab -txhais duab nrog tiag- lub sijhawm ultrasound dluab thaum lub sijhawm txheej txheem, ua tiav peb -dimensional visualization of the lesion and realtime puncture}. Qhov no muab cov kev xav tau tshiab ntawm cov koob tshuaj biopsy: rab koob yuav tsum muaj qhov pom kev pom zoo dua qub (xws li muaj zog ultrasound echo lossis CT imaging markers), thiab txawm muab cov khoom siv hluav taws xob me me los yog cov khoom siv fiber ntau los ua ib feem ntawm cov txheej txheem navigation, ua kom pom tseeb ntawm "qhov twg koob mus, daim duab qhia qhov twg".
Txoj Kev 2: Los ntawm ib txwm histology mus rau ntau -omics qauv yuav tsum tau ua. Nrog rau kev siv dav dav ntawm kev faib tawm molecular thiab kev kho mob rau cov kab mob xws li hepatocellular carcinoma, qhov kev thov kho mob rau kev kuaj ntshav biopsy tau tshaj li cov kab mob pathological morphology (histology). Cov kws kho mob xav tau kom txaus thiab siab - cov ntaub so ntswg zoo rau ntau- omics soj ntsuam xws li gene sequencing, proteomics, thiab immunohistochemistry. Qhov no yuav tsum tau siv rab koob biopsy los xyuas kom meej qhov kev ncaj ncees ntawm cov ntaub so ntswg strips thaum lub sij hawm tau txais cov qauv, txo cov neeg kho tshuab compression thiab thermal puas ntau li ntau tau, thiab tswj cov kev ua ntawm lom molecules. Nyob rau hauv lub neej yav tom ntej, tej zaum yuav muaj cov koob tshuaj biopsy / cov txheej txheem tshwj xeeb uas tsim los rau "molecular biopsy" nrog cryoprotection los yog tshwj xeeb preservation media.
Trend 3: The Rise of Robot-Assisted Biopsy. Surgical robots txuas ntxiv mus rau hauv thaj chaw ntawm kev cuam tshuam kev kuaj mob. Tus neeg hlau-pab biopsy system tuaj yeem tshem tawm kev tshee los ntawm tib neeg txhais tes thiab ua tiav cov punctures ruaj khov ntawm qib - millimeters, tshwj xeeb tshaj yog haum rau cov kab mob nyob ze cov hlab ntsha tseem ceeb, cov kab mob diaphragm, thiab lwm qhov chaw txaus ntshai. Cov neeg tsim khoom yuav tsum xav txog yuav ua li cas los tsim cov koob txhaj tshuaj tshwj xeeb uas tuaj yeem cuam tshuam nrog tus neeg hlau cov cuab yeej cuab tam thiab yooj yim rau cov neeg hlau tuav thiab ua haujlwm. Qhov no yuav suav nrog kev kho dua tshiab ntawm lub koob tuav, cov khoom siv (rau cov khoom tiv thaiv- plam), thiab hluav taws xob sib cuam tshuam (xws li ua rau lub tshuab tua hluav taws).
Trend 4: Complementarity ntawm kua biopsy thiab percutaneous biopsy. Txawm hais tias cov kua biopsy (uas pom cov qog DNA nyob hauv cov ntshav, thiab lwm yam) tab tom txhim kho sai, nyob rau hauv daim siab kab mob, tshwj xeeb tshaj yog nyob rau hauv kev kuaj mob ntawm daim siab mob cancer nyob rau hauv cov ntsiab lus ntawm daim siab cirrhosis, cov ntaub so ntswg biopsy tseem muaj irreplaceable nqi nyob rau hauv cov nqe lus ntawm spatial heterogeneity ntsuam xyuas thiab pathological kev pom zoo. Nyob rau hauv lub neej yav tom ntej, nws muaj feem ntau yuav yog ib tug qauv ntawm "kua biopsy raws li kev tshuaj ntsuam thawj zaug + imaging localization + meej puncture biopsy rau kev kuaj mob". Cov neeg tsim khoom tuaj yeem tsim cov phiaj xwm puncture uas sib haum nrog cov kua biopsy gene panels, piv txwv li, ua cov qauv ntsuas hauv cov cheeb tsam tshwj xeeb uas muaj qhov tshwm sim ntau ntawm cov noob hloov pauv.
Nyob rau hauv lub ntsej muag ntawm cov qauv no, txoj kev tsim kho tshiab rau cov tuam txhab kev phais mob me me yog qhov tseeb tab sis nyuaj: los ntawm kev tsim cov "cov cuab yeej cais tawm" los ua cov khoom lag luam thiab cov tsim kev daws teeb meem rau "kev kuaj xyuas meej". Qhov no txhais tau tias manufacturers yuav tsum tau:
* Tsim tus ntoo khaub lig- ciam teb R&D muaj peev xwm: Koom tes nrog cov tuam txhab khoom siv duab, tuam txhab neeg hlau, thiab cov tuam txhab tshuaj ntsuam xyuas molecular kom nkag siab txog kev sib cuam tshuam ntawm tag nrho cov kab mob.
* Layout cov ntaub ntawv thiab kev siv thev naus laus zis: Tsim cov ntaub ntawv sib xyaw tshiab thiab tsim cov khoom siv rau kev kos duab, thiab tshawb nrhiav qhov muaj peev xwm ntawm kev sib xyaw micro sensors hauv micro koob.
* Muab cov ntaub ntawv thiab kev txawj ntse: Xav txog yuav ua li cas los txheeb xyuas txhua qhov kev ua haujlwm biopsy (koob qhov tob, lub kaum sab xis, tus nqi siab tsis zoo) nrog rau cov qauv zoo thiab kuaj pom, thiab siv cov ntaub ntawv los txhim kho cov khoom tsim thiab cov txheej txheem ua haujlwm.
Qhov zoo ntawm Menghini koob yog nyob rau hauv nws lub peev xwm los daws cov teeb meem kev kho mob nyuaj uas siv cov ntsiab lus ntawm lub cev yooj yim. Nws lub neej yav tom ntej, txawm li cas los xij, nyob ntawm seb nws puas tuaj yeem koom ua ke rau hauv ib qho kev txawj ntse, meej dua thiab cov ntaub ntawv-nplua nuj kev kho mob niaj hnub. Qhov no xav kom cov tuam txhab tsim khoom tsis yog tsuas yog muaj lub siab zoo xwb, tab sis kuj yuav tsum muaj lub zeem muag thiab lub siab tawv kom txais kev hloov pauv thiab txuas nrog lub neej yav tom ntej.