Hauv kev kho mob brachytherapy, lub hauv paus tseem ceeb ntawm kev siv hluav taws xob zoo tshaj plaws, cov koob kho mob ua haujlwm ua lub cev ib leeg xa cov khoom siv hluav taws xob rau cov qog nqaij hlav. Lub raj xaim hlau no yog ua haujlwm nrog kev nkag mus rau cov ntaub so ntswg ib txwm nyob hauv cov duab taw qhia, ua tiav qhov chaw raug, thiab ua kom cov khoom siv hluav taws xob nyob ruaj khov lossis tso tawm hluav taws xob ntawm qhov chaw tau txiav txim siab. Kev ntseeg siab ntawm nws qhov kev ua tau zoo cuam tshuam ncaj qha rau kev xa xov tooj cua kom raug, kev tiv thaiv ntawm cov ntaub so ntswg noj qab haus huv, thiab kev nyab xeeb ntawm kev kho neeg mob. Lub hauv paus tseem ceeb uas txhais tau tias nws qhov kev txwv tsis pub ua haujlwm thiab cov hauv paus kev nyab xeeb yog nyob hauv nws cov ntaub ntawv tseem ceeb. Cov kws kho mob koob tshuaj brachytherapy ua cov kev xaiv zoo thiab ua cov txheej txheem kho mob qib stainless hlau thiab titanium alloys. Nyob deb tshaj qhov yooj yim tus nqi-cov txiaj ntsig kev lag luam tawm, qhov no sawv cev rau kev sib koom ua ke raws li hluav taws xob physics, biocompatibility, mechanical engineering thiab implantation kev nyab xeeb mus sij hawm ntev, aiming los tsim kom muaj kev ruaj ntseg, txhim khu kev qha thiab bio-phooj ywg xa tuaj rau txhua qhov kev sib tham high-dose irradiation.

Kev kho mob-qib stainless hlau, tshwj xeeb tshaj yog 316L lossis qib siab dua austenitic stainless hlau, yog cov khoom siv dav tshaj plaws thiab cov khoom siv classic rau cov koob tshuaj brachytherapy. Cov neeg tsim khoom 'kev nyiam mus ntev rau nws yog los ntawm nws qhov sib npaug ntawm lub zog, machinability, nqi-zoo thiab nruab nrab biocompatibility. Rau cov koob interstitial uas yuav tsum tau rov ua dua qhov chaw los yog qhov chaw nyob ib ntus thaum kho (xws li cov siv hauv kev siv tshuaj ntau ntau tom qab kev thauj khoom), lub siab rigidity thiab superior hnav tsis kam ntawm stainless hlau yog qhov tseem ceeb. Nws yuav tsum tau tiv thaiv los ntawm cov ntaub so ntswg thiab cov pob txha muaj peev xwm thaum lub sij hawm puncture, tuav lub preset koob insertion trajectory, thiab tsis txhob khoov los yog sib txawv - qhov tseem ceeb rau kev paub meej cov tshuaj faib tawm los ntawm Txoj Kev Npaj Kho Mob (TPS). Nws txoj kev tiv thaiv corrosion zoo tiv thaiv kev yaig los ntawm cov kua dej hauv cov ntaub so ntswg thiab cov tshuaj tua kab mob, ua kom muaj kev ruaj ntseg thaum lub sij hawm ib zaug lossis kev siv tsawg. Tsis tas li ntawd, cov txheej txheem machining stainless hlau paub tab pab tsim cov cannulas nrog cov phab ntsa zoo nkauj thiab qhov ntev me me ntawm kev kos duab, sib tsoo thiab polishing. Qhov no yog qhov tseem ceeb rau kev txav mus los, qhov tseeb qhov chaw thiab tshem tawm ntawm cov khoom siv hluav taws xob (xws li, Iridium-192 qhov chaw xaim) hauv cannulas, ncaj qha txiav txim siab qhov tseeb ntawm kev xa tshuaj.

Txawm li cas los xij, thaum kho qhov xwm txheej cuam tshuam nrog kev cog qoob loo mus tas li, xws li Iodine-125 noob cog rau kev mob qog noj ntshav, cov khoom siv mus sij hawm ntev biocompatibility thiab cov duab sib raug zoo yog qhov txiav txim siab. Hauv cov xwm txheej zoo li no, titanium alloy sawv ua cov khoom siv tsis sib haum xeeb ntawm kev xaiv. Qhov zoo tshaj plaws ntawm titanium alloy yog nws cov kev tsis sib haum xeeb tsis sib xws thiab kev sib raug zoo nrog tib neeg cov ntaub so ntswg. The dense titanium‑oxide passive film spontaneously formed on its surface features extremely stable chemical properties, effectively blocking metal‑ion release and virtually eliminating inflammation, allergies or tissue rejection reactions that may arise after long‑term implantation. Qhov no ua hauj lwm raws li ib qho kev nyab xeeb yam yuav tsum tau ua ua ntej rau radioactive noob casings npaj rau indwelling nyob rau hauv tib neeg lub cev. Raws li kev txheeb xyuas los ntawm kev tshawb fawb, cov noob casings rau encapsulating Iodine-125 yog tsim los ntawm titanium raj. Lawv cov phab ntsa thickness yog xam tau los lav kom txaus txhua yam lub zog tsis ua rau muaj hluav taws xob ntau dhau.

Tshaj li biocompatibility, lwm qhov zoo dua ntawm titanium alloy rau daim ntawv thov kev cog qoob loo mus tas li yog nws cov khoom tsis yog ferromagnetic. Tom qab kev kho mob, cov neeg mob yuav tsum tau kuaj MRI los ntsuas kev kho mob los yog saib xyuas lwm yam mob. Titanium alloy implants ua kom tsis muaj kev hloov pauv lossis cua sov hauv thaj chaw muaj zog sib nqus thiab ua rau cov duab kos tsawg kawg nkaus, kom ntseeg tau qhov ua tau thiab pom tseeb ntawm cov duab tom ntej. Txawm hais tias cov khoom siv raw thiab cov nqi ua rau titanium alloy tshaj cov hlau tsis muaj steel, nws ua cov khoom tseem ceeb rau kev tsim cov khoom tseem ceeb hauv kev sib tw hauv cov ntawv cog lus ruaj khov uas ua raws li kev nyab xeeb mus sij hawm ntev thiab tsis txhob muaj kev cuam tshuam txog kev lom neeg.

Cov neeg tsim khoom cov kev txawj ntse yog ntxiv los ntawm kev siv qhov tob ntawm cov khoom siv nrog rau kev ua kom zoo dua qub. Txawm hais tias stainless hlau los yog titanium alloy, raw cov ntaub ntawv purity thiab sib xws yog cov txheej txheem kev tshuaj ntsuam. Cov ntaub ntawv kho mob tau txwv nruj rau cov khoom tsis huv xws li carbon, sulfur thiab phosphorus. Tom ntej no precision machining, xws li multi-axis CNC sib tsoo, xyuas kom meej cov lus qhia muaj qhov zoo tshaj plaws bevel kaum sab xis thiab txiav-ntug sharpness kom txo tau puncture kuj thiab cov ntaub so ntswg raug mob. Cov txheej txheem nto tiav nrog rau electrolytic polishing tshem tawm cov micro-burrs thiab ua rau ob sab hauv thiab sab nrauv cannula phab ntsa iav-smooth. Qhov no tsis tsuas yog txo cov ntaub so ntswg kev sib txhuam thaum lub sij hawm puncture tab sis kuj ua kom tsis muaj kev cuam tshuam txoj hauv kev rau cov khoom siv hluav taws xob, tiv thaiv qhov chaw xaim cuam tshuam los ntawm cov phab ntsa ntawm lub raj tsis zoo - txoj sia ntawm kev kho mob kev nyab xeeb thiab kev txhaj tshuaj raug.

Yog li ntawd, cov tuam txhab kev koom tes sib sib zog nqus hauv cov ntaub ntawv kev tshawb fawb rau cov koob tshuaj brachytherapy tseem ceeb txhais cov khoom siv-science yam ntxwv rau kev txiav txim siab kom muaj nuj nqis thiab kev nyab xeeb hauv kev kho mob hluav taws xob. Los ntawm kev nkag siab zoo thiab sib txawv ntawm daim ntawv thov ntawm stainless hlau thiab titanium alloy, lawv muab hluav taws xob oncologists thiab cov kws kho mob physicists nrog cov cuab yeej txhim khu kev qha uas hloov tau rau ntau hom kev kho mob (ib ntus interstitial implantation vs. implantation mus tas li) thiab ntau yam kev xav tau kev kho mob. Cov koob zoo no tsis yog tsuas yog lub cev ua haujlwm ntawm kev xa hluav taws xob nkaus xwb tab sis kuj cov tuam txhab kev cog lus rau kev xa hluav taws xob xoo hluav taws xob thiab lub luag haujlwm siab rau cov neeg mob kev noj qab haus huv mus sij hawm ntev. Nyob rau hauv lub era ntawm precision xov tooj cua kho mob, cov ntaub ntawv pab raws li lub cev lub hauv paus pob zeb ua kom muaj kev nyab xeeb ntawm tag nrho cov high-dose, high-precision kev kho mob.